Prof. Dr. M. Hoch
Chair of Molecular Developmental Biology
Life & Medical Sciences Institute (LIMES)
Development, Genetics &
Molecular Physiology Unit
University of Bonn
Meckenheimer Allee 169
D - 53115 Bonn
+49/(0)2 28/73-44 09 m.hoch@uni-bonn.de
Our group is part of the Life & Medical Sciences Institute (LIMES) of the University of Bonn. We are interested in the molecular mechanisms of cell-to-cell communication and on the regulation of cellular growth and metabolism during tissue and organ formation in Drosophila.
In particular, our projects focus on the crossregulation of cell growth, ageing and innate immunity, on direct cell communcation mediated by the innexin family of gap junction channel proteins, on lipid metabolism and obesity, and recent studies have raised our interest in endocytosis-dependent airway physiology. Using genetic screens in the fruit fly Drosophila, we have identified in the last years new key regulators some of which have single orthologs in mice and humans and we are starting to analyse their role in mouse models.
Our projects which are funded by the German Research Foundation (DFG) are part of the Collaborative Research Center SFB 645 on lipid/protein-interactions in membranes (Speaker: M. Hoch) and the Collaborative Research Center SFB 704 on local immunity (Speaker: W. Kolanus, LIMES Institute). Furthermore our projects are integrated into the Research Training Group 804 (Speaker: M. Famulok).
Our teaching duties include courses, seminars and lectures on Molecular Developmental Biology and Developmental Genetics in the study programs Molecular Biomedicine and Biology. In addition, we participate in a new summer study program Life Sciences & Culture Bonn for undergraduate students which was started in summer 2006 together with Harvard University (USA). Currently, we are involved in the organization of the international graduate school “Life & Medical Sciences ” of the LIMES Institute.
NEW:
November 03, 2009:
Paper in EMBO Journal on Schlank that controls growth and body fat
Presseartikel der Uni Bonn
March 11, 2008:
Paper in Nature Cell Biology on Wech and its role in muscle attachment,
Presseartikel Uni-Bonn
June 10, 2007:
Paper in Nature Cell Biology on Wurst and its role in the conversion from liquid- to air-filling in the airways
Press release
